Debra L. Laskin, Ph.D.
Vesicant-induced Pulmonary Injury
Distinguished Professor & Chair, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University
Recent Publications
Pappas, G, Gardner, C, Guo, C, Black, K, Rancourt, R, Laskin, D, Kipen, H, Sotolongo, A, Falvo, M, Gow, A. Monocyte clusters suggestive of a chronic inflammatory phenotype are associated with reduced endothelial function in Veterans with respiratory symptoms. PLoS One. 2026;21 (2):e0338883. PubMed PMID:41666147 PubMed Central PMC12890113.
Sunil, VR, Vayas, KN, Radbel, J, Smith, LC, Meshanni, JA, Lee, JM, Weinstock, D, Abramova, E, Shmarakov, IO, Gow, AJ, Laskin, JD, Laskin, DL. Lung injury, oxidative stress, and impaired functioning in a model of prolonged ozone exposure in female mice are associated with macrophage proinflammatory and profibrotic activation and altered bioenergetics. Toxicol Sci. 2026;209 (2):. PubMed PMID:41390972 .
Seymore, T, Guo, C, Bellomo, A, Herbert, J, Laskin, D, Gow, A, Stapleton, P. Inhalation of titanium dioxide nanoparticles during gestation alters placental bioenergetics in a sex-related manner in rats. Placenta. 2025;168 :168-176. PubMed PMID:40592188 PubMed Central PMC12291600.
Lee, JM, Meshanni, JA, Vayas, KN, Sunil, VR, Radbel, J, Laskin, JD, Laskin, DL, Gow, AJ. Inhaled ozone induces distinct alterations in pulmonary function in models of acute and episodic exposure in female mice. Toxicol Sci. 2025;204 (1):70-78. PubMed PMID:39798125 PubMed Central PMC11879009.
Aggarwal, T, Bellomo, A, Stevenson, ER, Herbert, J, Laskin, DL, Gow, AJ, Izgu, EC. Protocol for detecting nitrative stress in biological lipid membranes in murine cells and tissues. STAR Protoc. 2024;5 (3):103268. PubMed PMID:39215997 PubMed Central PMC11403049.
Armeli, F, Mengoni, B, Laskin, DL, Businaro, R. Interplay among Oxidative Stress, Autophagy, and the Endocannabinoid System in Neurodegenerative Diseases: Role of the Nrf2- p62/SQSTM1 Pathway and Nutraceutical Activation. Curr Issues Mol Biol. 2024;46 (7):6868-6884. PubMed PMID:39057052 PubMed Central PMC11276139.
Aleksunes, LM, Gray, JP, Meshanni, J, Laskin, JD, Laskin, DL. Repurposing FDA-approved drugs to treat chemical weapon toxicities: Interactive case studies for trainees. Pharmacol Res Perspect. 2024;12 (4):e1229. PubMed PMID:38965070 PubMed Central PMC11223991.
Smith, LC, Abramova, E, Vayas, K, Rodriguez, J, Gelfand-Titiyevksiy, B, Roepke, TA, Laskin, JD, Gow, AJ, Laskin, DL. Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation. Toxicol Sci. 2024;201 (1):103-117. PubMed PMID:38897669 PubMed Central PMC11347782.
Radbel, J, Meshanni, JA, Vayas, KN, Le-Hoang, O, Abramova, E, Zhou, P, Joseph, LB, Laskin, JD, Gow, AJ, Laskin, DL. Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia. Toxicol Sci. 2024;200 (2):299-311. PubMed PMID:38749002 PubMed Central PMC11285192.
Bellomo, A, Herbert, J, Kudlak, MJ, Laskin, JD, Gow, AJ, Laskin, DL. Identification of early events in nitrogen mustard pulmonary toxicity that are independent of infiltrating inflammatory cells using precision cut lung slices. Toxicol Appl Pharmacol. 2024;486 :116941. PubMed PMID:38677601 PubMed Central PMC11887942.
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