Debra L. Laskin, Ph.D.
Vesicant-induced Pulmonary Injury
Distinguished Professor & Chair, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University
Recent Publications
Armeli, F, Mengoni, B, Laskin, DL, Businaro, R. Interplay among Oxidative Stress, Autophagy, and the Endocannabinoid System in Neurodegenerative Diseases: Role of the Nrf2- p62/SQSTM1 Pathway and Nutraceutical Activation. Curr Issues Mol Biol. 2024;46 (7):6868-6884. PubMed PMID:39057052 .
Aleksunes, LM, Gray, JP, Meshanni, J, Laskin, JD, Laskin, DL. Repurposing FDA-approved drugs to treat chemical weapon toxicities: Interactive case studies for trainees. Pharmacol Res Perspect. 2024;12 (4):e1229. PubMed PMID:38965070 PubMed Central PMC11223991.
Smith, LC, Abramova, H, Vayas, K, Rodriguez, J, Gelfand-Titiyevksiy, B, Roepke, T, Laskin, JD, Gow, AJ, Laskin, DL. Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation. Toxicol Sci. 2024; :. PubMed PMID:38897669 .
Radbel, J, Meshanni, JA, Vayas, KN, Le-Hoang, O, Abramova, E, Zhou, P, Joseph, LB, Laskin, JD, Gow, AJ, Laskin, DL. Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of non-pneumonic endotoxemia. Toxicol Sci. 2024; :. PubMed PMID:38749002 .
Bellomo, A, Herbert, J, Kudlak, MJ, Laskin, JD, Gow, AJ, Laskin, DL. Identification of early events in nitrogen mustard pulmonary toxicity that are independent of infiltrating inflammatory cells using precision cut lung slices. Toxicol Appl Pharmacol. 2024;486 :116941. PubMed PMID:38677601 .
Malaviya, R, Meshanni, JA, Sunil, VR, Venosa, A, Guo, C, Abramova, EV, Vayas, KN, Jiang, C, Cervelli, JA, Gow, AJ, Laskin, JD, Laskin, DL. Role of macrophage bioenergetics in N-acetylcysteine-mediated mitigation of lung injury and oxidative stress induced by nitrogen mustard. Toxicol Appl Pharmacol. 2024;485 :116908. PubMed PMID:38513841 .
Gutierrez, B, Aggarwal, T, Erguven, H, Stone, MRL, Guo, C, Bellomo, A, Abramova, E, Stevenson, ER, Laskin, DL, Gow, AJ, Izgu, EC. Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite. iScience. 2023;26 (12):108567. PubMed PMID:38144454 PubMed Central PMC10746523.
Laskin, JD, Ozkuyumcu, K, Zhou, P, Croutch, CR, Heck, DE, Laskin, DL, Joseph, LB. Skin Models Used to Define Mechanisms of Action of Sulfur Mustard. Disaster Med Public Health Prep. 2023;17 :e551. PubMed PMID:37849329 .
Malaviya, R, Laskin, JD, Businaro, R, Laskin, DL. Targeting Tumor Necrosis Factor Alpha to Mitigate Lung Injury Induced by Mustard Vesicants and Radiation. Disaster Med Public Health Prep. 2023;17 :e553. PubMed PMID:37848400 PubMed Central PMC10841250.
Smith, LC, Gow, AJ, Abramova, E, Vayas, K, Guo, C, Noto, J, Lyman, J, Rodriquez, J, Gelfand-Titiyevskiy, B, Malcolm, C, Laskin, JD, Laskin, DL. Role of PPARγ in dyslipidemia and altered pulmonary functioning in mice following ozone exposure. Toxicol Sci. 2023;194 (1):109-119. PubMed PMID:37202362 PubMed Central PMC10306402.
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