Debra L. Laskin, Ph.D.
Vesicant-induced Pulmonary Injury
Distinguished Professor & Chair, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University
Recent Publications
Cody Smith, L, Gow, AJ, Abramova, E, Vayas, K, Guo, C, Noto, J, Lyman, J, Rodriquez, J, Gelfand-Titiyevskiy, B, Malcolm, C, Laskin, JD, Laskin, DL. Role of PPARγ in dyslipidemia and altered pulmonary functioning in mice following ozone exposure. Toxicol Sci. 2023; :. PubMed PMID:37202362 .
Meshanni, JA, Lee, JM, Vayas, KN, Sun, R, Jiang, C, Guo, GL, Gow, AJ, Laskin, JD, Laskin, DL. Suppression of lung oxidative stress, inflammation and fibrosis following nitrogen mustard exposure by the selective farnesoid X receptor agonist obeticholic acid. J Pharmacol Exp Ther. 2023; :. PubMed PMID:37188530 .
Cary, CM, Seymore, TN, Singh, D, Vayas, KN, Goedken, MJ, Adams, S, Polunas, M, Sunil, VR, Laskin, DL, Demokritou, P, Stapleton, PA. Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats. Part Fibre Toxicol. 2023;20 (1):16. PubMed PMID:37088832 PubMed Central PMC10122824.
Gowdy, KM, Laskin, DL. Resolution of inflammation in xenobiotic-induced mucosal injury and chronic disease. Toxicol Appl Pharmacol. 2023;466 :116455. PubMed PMID:36907382 .
Herbert, J, Kelty, JS, Laskin, JD, Laskin, DL, Gow, AJ. Menthol flavoring in e-cigarette condensate causes pulmonary dysfunction and cytotoxicity in precision cut lung slices. Am J Physiol Lung Cell Mol Physiol. 2023;324 (3):L345-L357. PubMed PMID:36692165 PubMed Central PMC10026991.
Malaviya, R, Gardner, CR, Rancourt, RC, Smith, LC, Abramova, EV, Vayas, KN, Gow, AJ, Laskin, JD, Laskin, DL. Lung injury and oxidative stress induced by inhaled chlorine in mice is associated with proinflammatory activation of macrophages and altered bioenergetics. Toxicol Appl Pharmacol. 2023;461 :116388. PubMed PMID:36690086 PubMed Central PMC9960611.
Radbel, J, Meshanni, JA, Gardner, CR, Le-Hoang, O, Cervelli, J, Laskin, JD, Gow, AJ, Laskin, DL. Novel method to assess resident alveolar macrophage efferocytosis of apoptotic neutrophils by flow cytometry. Toxicol Appl Pharmacol. 2023;460 :116359. PubMed PMID:36565939 PubMed Central PMC9870943.
Taylor, S, Murray, A, Francis, M, Abramova, E, Guo, C, Laskin, DL, Gow, AJ. Regulation of macrophage activation by S-Nitrosothiols following ozone-induced lung injury. Toxicol Appl Pharmacol. 2022;457 :116281. PubMed PMID:36244437 .
Sunil, VR, Vayas, KN, Radbel, J, Abramova, E, Gow, A, Laskin, JD, Laskin, DL. Impaired energy metabolism and altered functional activity of alveolar type II epithelial cells following exposure of rats to nitrogen mustard. Toxicol Appl Pharmacol. 2022;456 :116257. PubMed PMID:36174670 .
Murray, A, Banota, T, Guo, GL, Smith, LC, Meshanni, JA, Lee, J, Kong, B, Abramova, EV, Goedken, M, Gow, AJ, Laskin, JD, Laskin, DL. Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure. Toxicol Appl Pharmacol. 2022;454 :116208. PubMed PMID:35998709 PubMed Central PMC9960619.
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