Robert Casillas, Ph.D.
Investigator
Director, Nonclinical Consulting, Latham BioPharm Group
Recent Publications
Malaviya, R, Bellomo, A, Abramova, E, Croutch, CR, Roseman, J, Tuttle, R, Peters, E, Casillas, RP, Sunil, VR, Laskin, JD, Laskin, DL. Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody. Toxicol Appl Pharmacol. 2021;428 :115677. PubMed PMID:34390737 PubMed Central PMC8452183.
Casillas, RP, Tewari-Singh, N, Gray, JP. Special issue: emerging chemical terrorism threats. Toxicol Mech Methods. 2021;31 (4):239-241. PubMed PMID:33730980 PubMed Central PMC10728888.
Malaviya, R, Abramova, EV, Rancourt, RC, Sunil, VR, Napierala, M, Weinstock, D, Croutch, CR, Roseman, J, Tuttle, R, Peters, E, Casillas, RP, Laskin, JD, Laskin, DL. Progressive Lung Injury, Inflammation, and Fibrosis in Rats Following Inhalation of Sulfur Mustard. Toxicol Sci. 2020;178 (2):358-374. PubMed PMID:33002157 PubMed Central PMC7751178.
Hobson, ST, Casillas, RP, Richieri, RA, Nishimura, RN, Weisbart, RH, Tuttle, R, Reynolds, GT, Parseghian, MH. Development of an acute, short-term exposure model for phosgene. Toxicol Mech Methods. 2019;29 (8):604-615. PubMed PMID:31237465 PubMed Central PMC6715518.
Chang, YC, Soriano, M, Hahn, RA, Casillas, RP, Gordon, MK, Laskin, JD, Gerecke, DR. Expression of cytokines and chemokines in mouse skin treated with sulfur mustard. Toxicol Appl Pharmacol. 2018;355 :52-59. PubMed PMID:29935281 PubMed Central PMC6438172.
Joseph, LB, Composto, GM, Perez, RM, Kim, HD, Casillas, RP, Heindel, ND, Young, SC, Lacey, CJ, Saxena, J, Guillon, CD, Croutch, CR, Laskin, JD, Heck, DE. Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug. Toxicol Lett. 2018;293 :77-81. PubMed PMID:29127031 PubMed Central PMC5938161.
Tewari-Singh, N, Goswami, DG, Kant, R, Ammar, DA, Kumar, D, Enzenauer, RW, Casillas, RP, Croutch, CR, Petrash, JM, Agarwal, R. Histopathological and Molecular Changes in the Rabbit Cornea From Arsenical Vesicant Lewisite Exposure. Toxicol Sci. 2017;160 (2):420-428. PubMed PMID:28973427 PubMed Central PMC5837587.
Tewari-Singh, N, Goswami, DG, Kant, R, Croutch, CR, Casillas, RP, Orlicky, DJ, Agarwal, R. Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity. Toxicol Appl Pharmacol. 2017;317 :25-32. PubMed PMID:28087322 .
Composto, GM, Laskin, JD, Laskin, DL, Gerecke, DR, Casillas, RP, Heindel, ND, Joseph, LB, Heck, DE. Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug. Exp Mol Pathol. 2016;100 (3):522-31. PubMed PMID:27189522 PubMed Central PMC4947376.
Wohlman, IM, Composto, GM, Heck, DE, Heindel, ND, Lacey, CJ, Guillon, CD, Casillas, RP, Croutch, CR, Gerecke, DR, Laskin, DL, Joseph, LB, Laskin, JD. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. Toxicol Appl Pharmacol. 2016;303 :30-44. PubMed PMID:27125198 PubMed Central PMC4947375.
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