Patrick Sinko, Ph.D.Patrick Sinko

Pharmaceutics
Distinguished Professor, Parke-Davis Endowed Chair, Pharmaceutics; Ernest Mario School of Pharmacy, Rutgers University

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Recent Publications

Joseph, LB, Gordon, MK, Zhou, P, Hahn, RA, Lababidi, H, Croutch, CR, Sinko, PJ, Heck, DE, Laskin, DL, Laskin, JD. Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix. Exp Mol Pathol. 2022;128 :104807. PubMed PMID:35798063 .

Sandhu, SK, Kumar, S, Raut, J, Singh, M, Kaur, S, Sharma, G, Roldan, TL, Trehan, S, Holloway, J, Wahler, G, Laskin, JD, Sinko, PJ, Berthiaume, F, Michniak-Kohn, B, Rishi, P, Ganesh, N, Kaur, IP. Systematic Development and Characterization of Novel, High Drug-Loaded, Photostable, Curcumin Solid Lipid Nanoparticle Hydrogel for Wound Healing. Antioxidants (Basel). 2021;10 (5):. PubMed PMID:34063003 PubMed Central PMC8148018.

Al-Zubaydi, F, Gao, D, Kakkar, D, Li, S, Holloway, J, Szekely, Z, Chan, N, Kumar, S, Sabaawy, HE, Love, S, Sinko, PJ. Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy. Drug Deliv Transl Res. 2022;12 (1):240-256. PubMed PMID:33590464 .

Wilson, BK, Sinko, PJ, Prud'homme, RK. Encapsulation and Controlled Release of a Camptothecin Prodrug from Nanocarriers and Microgels: Tuning Release Rate with Nanocarrier Excipient Composition. Mol Pharm. 2021;18 (3):1093-1101. PubMed PMID:33440941 .

Laskin, JD, Wahler, G, Croutch, CR, Sinko, PJ, Laskin, DL, Heck, DE, Joseph, LB. Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Exp Mol Pathol. 2020;115 :104470. PubMed PMID:32445752 PubMed Central PMC7374066.

Al-Zubaydi, F, Gao, D, Kakkar, D, Li, S, Adler, D, Holloway, J, Szekely, Z, Gu, Z, Chan, N, Kumar, S, Love, S, Sinko, PJ. Breast intraductal nanoformulations for treating ductal carcinoma in situ I: Exploring metal-ion complexation to slow ciclopirox release, enhance mammary persistence and efficacy. J Control Release. 2020;323 :71-82. PubMed PMID:32302762 .

Chen, P, Zhang, X, Venosa, A, Lee, IH, Myers, D, Holloway, JA, Prud'homme, RK, Gao, D, Szekely, Z, Laskin, JD, Laskin, DL, Sinko, PJ. A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages. Pharmaceutics. 2020;12 (3):. PubMed PMID:32182675 PubMed Central PMC7150811.

Gu, Z, Al-Zubaydi, F, Adler, D, Li, S, Johnson, S, Prasad, P, Holloway, J, Szekely, Z, Love, S, Gao, D, Sinko, PJ. Evaluation of intraductal delivery of poly(ethylene glycol)-doxorubicin conjugate nanocarriers for the treatment of ductal carcinoma in situ (DCIS)-like lesions in rats. J Interdiscip Nanomed. 2018;3 (3):146-159. PubMed PMID:30443411 PubMed Central PMC6220801.

Heon Lee, I, Palombo, MS, Zhang, X, Szekely, Z, Sinko, PJ. Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery. Eur J Pharm Biopharm. 2019;138 :11-22. PubMed PMID:29894816 PubMed Central PMC6286870.

Gu, Z, Gao, D, Al-Zubaydi, F, Li, S, Singh, Y, Rivera, K, Holloway, J, Szekely, Z, Love, S, Sinko, PJ. The effect of size and polymer architecture of doxorubicin-poly(ethylene) glycol conjugate nanocarriers on breast duct retention, potency and toxicity. Eur J Pharm Sci. 2018;121 :118-125. PubMed PMID:29698706 .

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