Patrick Sinko, Ph.D.Patrick Sinko

Pharmaceutics
Distinguished Professor, Parke-Davis Endowed Chair, Pharmaceutics; Ernest Mario School of Pharmacy, Rutgers University

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Recent Publications

Sandhu, SK, Kumar, S, Raut, J, Singh, M, Kaur, S, Sharma, G, Roldan, TL, Trehan, S, Holloway, J, Wahler, G, Laskin, JD, Sinko, PJ, Berthiaume, F, Michniak-Kohn, B, Rishi, P, Ganesh, N, Kaur, IP. Systematic Development and Characterization of Novel, High Drug-Loaded, Photostable, Curcumin Solid Lipid Nanoparticle Hydrogel for Wound Healing. Antioxidants (Basel). 2021;10 (5):. PubMed PMID:34063003 PubMed Central PMC8148018.

Al-Zubaydi, F, Gao, D, Kakkar, D, Li, S, Holloway, J, Szekely, Z, Chan, N, Kumar, S, Sabaawy, HE, Love, S, Sinko, PJ. Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy. Drug Deliv Transl Res. 2022;12 (1):240-256. PubMed PMID:33590464 .

Wilson, BK, Sinko, PJ, Prud'homme, RK. Encapsulation and Controlled Release of a Camptothecin Prodrug from Nanocarriers and Microgels: Tuning Release Rate with Nanocarrier Excipient Composition. Mol Pharm. 2021;18 (3):1093-1101. PubMed PMID:33440941 .

Laskin, JD, Wahler, G, Croutch, CR, Sinko, PJ, Laskin, DL, Heck, DE, Joseph, LB. Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Exp Mol Pathol. 2020;115 :104470. PubMed PMID:32445752 PubMed Central PMC7374066.

Al-Zubaydi, F, Gao, D, Kakkar, D, Li, S, Adler, D, Holloway, J, Szekely, Z, Gu, Z, Chan, N, Kumar, S, Love, S, Sinko, PJ. Breast intraductal nanoformulations for treating ductal carcinoma in situ I: Exploring metal-ion complexation to slow ciclopirox release, enhance mammary persistence and efficacy. J Control Release. 2020;323 :71-82. PubMed PMID:32302762 .

Chen, P, Zhang, X, Venosa, A, Lee, IH, Myers, D, Holloway, JA, Prud'homme, RK, Gao, D, Szekely, Z, Laskin, JD, Laskin, DL, Sinko, PJ. A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages. Pharmaceutics. 2020;12 (3):. PubMed PMID:32182675 PubMed Central PMC7150811.

Gu, Z, Al-Zubaydi, F, Adler, D, Li, S, Johnson, S, Prasad, P, Holloway, J, Szekely, Z, Love, S, Gao, D, Sinko, PJ. Evaluation of intraductal delivery of poly(ethylene glycol)-doxorubicin conjugate nanocarriers for the treatment of ductal carcinoma in situ (DCIS)-like lesions in rats. J Interdiscip Nanomed. 2018;3 (3):146-159. PubMed PMID:30443411 PubMed Central PMC6220801.

Heon Lee, I, Palombo, MS, Zhang, X, Szekely, Z, Sinko, PJ. Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery. Eur J Pharm Biopharm. 2019;138 :11-22. PubMed PMID:29894816 PubMed Central PMC6286870.

Gu, Z, Gao, D, Al-Zubaydi, F, Li, S, Singh, Y, Rivera, K, Holloway, J, Szekely, Z, Love, S, Sinko, PJ. The effect of size and polymer architecture of doxorubicin-poly(ethylene) glycol conjugate nanocarriers on breast duct retention, potency and toxicity. Eur J Pharm Sci. 2018;121 :118-125. PubMed PMID:29698706 .

Dong, H, Ma, J, Wang, J, Wu, ZS, Sinko, PJ, Jia, L. A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells. Mol Ther Nucleic Acids. 2016;5 :e302. PubMed PMID:27045206 PubMed Central PMC5014519.

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