Donald R. Gerecke, Ph.D.
Co-Principal Investigator
Associate Professor, Pharmacology & Toxicology
Rutgers University
Recent Publications
DeSantis-Rodrigues, A, Hahn, RA, Zhou, P, Babin, M, Svoboda, KKH, Chang, YC, Gerecke, DR, Gordon, MK. SM1997 downregulates mustard-induced enzymes that disrupt corneal epithelial attachment. Anat Rec (Hoboken). 2021;304 (9):1974-1983. PubMed PMID:33554453 .
Chang, YC, Hahn, RA, Gordon, MK, Laskin, JD, Gerecke, DR. A type IV collagenase inhibitor, N-hydroxy-3-phenyl-2-(4-phenylbenzenesulfonamido) propanamide (BiPS), suppresses skin injury induced by sulfur mustard. Toxicol Appl Pharmacol. 2020;401 :115078. PubMed PMID:32479919 PubMed Central PMC7470515.
Chang, YC, Wang, JD, Chang, HY, Zhou, P, Hahn, RA, Gordon, MK, Laskin, JD, Gerecke, DR. Expression of Laminin γ2 Proteolytic Fragments in Murine Skin Following Exposure to Sulfur Mustard. Anat Rec (Hoboken). 2020;303 (6):1642-1652. PubMed PMID:32421930 PubMed Central PMC7394410.
Chang, YC, Gordon, MK, Gerecke, DR. Expression of Laminin 332 in Vesicant Skin Injury and Wound Repair. Clin Dermatol (Wilmington). 2018;2 (1):. PubMed PMID:30058002 PubMed Central PMC6063082.
Chang, YC, Soriano, M, Hahn, RA, Casillas, RP, Gordon, MK, Laskin, JD, Gerecke, DR. Expression of cytokines and chemokines in mouse skin treated with sulfur mustard. Toxicol Appl Pharmacol. 2018;355 :52-59. PubMed PMID:29935281 PubMed Central PMC6438172.
Gordon, MK, DeSantis-Rodrigues, A, Hahn, R, Zhou, P, Chang, Y, Svoboda, KK, Gerecke, DR. The molecules in the corneal basement membrane zone affected by mustard exposure suggest potential therapies. Ann N Y Acad Sci. 2016;1378 (1):158-165. PubMed PMID:27737494 PubMed Central PMC5221489.
Composto, GM, Laskin, JD, Laskin, DL, Gerecke, DR, Casillas, RP, Heindel, ND, Joseph, LB, Heck, DE. Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug. Exp Mol Pathol. 2016;100 (3):522-31. PubMed PMID:27189522 PubMed Central PMC4947376.
Wohlman, IM, Composto, GM, Heck, DE, Heindel, ND, Lacey, CJ, Guillon, CD, Casillas, RP, Croutch, CR, Gerecke, DR, Laskin, DL, Joseph, LB, Laskin, JD. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. Toxicol Appl Pharmacol. 2016;303 :30-44. PubMed PMID:27125198 PubMed Central PMC4947375.
DeSantis-Rodrigues, A, Chang, YC, Hahn, RA, Po, IP, Zhou, P, Lacey, CJ, Pillai, A, C Young, S, Flowers, RA 2nd, Gallo, MA, Laskin, JD, Gerecke, DR, Svoboda, KK, Heindel, ND, Gordon, MK. ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure. Invest Ophthalmol Vis Sci. 2016;57 (4):1687-98. PubMed PMID:27058125 PubMed Central PMC4829087.
Chang, YC, Wang, JD, Hahn, RA, Gordon, MK, Joseph, LB, Heck, DE, Heindel, ND, Young, SC, Sinko, PJ, Casillas, RP, Laskin, JD, Laskin, DL, Gerecke, DR. Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. Toxicol Appl Pharmacol. 2014;280 (2):236-44. PubMed PMID:25127551 PubMed Central PMC4254337.
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