Diane Heck, Ph.D.

Pharmacology & Drug Development
Professor & Associate Dean for Research, School of Health Sciences and Practice, New York Medical College

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Recent Publications

Jan, YH, Heck, DE, An, Y, Laskin, DL, Laskin, JD. Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes. Chem Res Toxicol. 2022;35 (4):636-650. PubMed PMID:35312310 .

Joseph, LB, Gordon, MK, Kang, J, Croutch, CR, Zhou, P, Heck, DE, Laskin, DL, Laskin, JD. Characterization of the rabbit conjunctiva: Effects of sulfur mustard. Exp Mol Pathol. 2021;121 :104656. PubMed PMID:34081961 PubMed Central PMC9006340.

Mishin, V, Heck, DE, Laskin, DL, Laskin, JD. The amplex red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxide in the presence of NAD(P)H. Free Radic Res. 2020;54 (8-9):620-628. PubMed PMID:32912004 PubMed Central PMC7874521.

Guillon, C, Vetrano, AM, Saxena, J, Hunter, A, Verderone, G, Finetti, TM, Wisnoski, J, DeMatteo, PW, Rapp, RD, Heindel, ND, Joseph, LB, Heck, DE, Laskin, JD. Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors. Bioorg Chem. 2020;103 :104128. PubMed PMID:32745761 PubMed Central PMC7819682.

Laskin, JD, Wahler, G, Croutch, CR, Sinko, PJ, Laskin, DL, Heck, DE, Joseph, LB. Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Exp Mol Pathol. 2020;115 :104470. PubMed PMID:32445752 PubMed Central PMC7374066.

Jan, YH, Heck, DE, Laskin, DL, Laskin, JD. DNA damage signaling in the cellular responses to mustard vesicants. Toxicol Lett. 2020;326 :78-82. PubMed PMID:32173488 PubMed Central PMC7224631.

Wahler, G, Heck, DE, Heindel, ND, Laskin, DL, Laskin, JD, Joseph, LB. Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard. Exp Mol Pathol. 2020;114 :104410. PubMed PMID:32113906 PubMed Central PMC7237310.

Guillon, C, Jan, YH, Heck, DE, Mariano, TM, Rapp, RD, Jetter, M, Kardos, K, Whittemore, M, Akyea, E, Jabin, I, Laskin, JD, Heindel, ND. Phototoxicity of 7-oxycoumarins with keratinocytes in culture. Bioorg Chem. 2019;89 :103014. PubMed PMID:31170642 PubMed Central PMC6656587.

Jan, YH, Heck, DE, Laskin, DL, Laskin, JD. Sulfur Mustard Analog Mechlorethamine (Bis(2-chloroethyl)methylamine) Modulates Cell Cycle Progression via the DNA Damage Response in Human Lung Epithelial A549 Cells. Chem Res Toxicol. 2019;32 (6):1123-1133. PubMed PMID:30964658 PubMed Central PMC6626495.

Guillon, CD, Jan, YH, Foster, N, Ressner, J, Heck, DE, Laskin, JD, Heindel, ND. Synthetically modified methoxsalen for enhanced cytotoxicity in light and dark reactions. Bioorg Med Chem Lett. 2019;29 (4):619-622. PubMed PMID:30638875 PubMed Central PMC6364570.

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