Diane Heck, Ph.D.

Pharmacology & Drug Development
Professor & Associate Dean for Research, School of Health Sciences and Practice, New York Medical College

[Link to Bio] [Back to Members Page]

Recent Publications

Mishin, V, Heck, DE, Jan, YH, Richardson, JR, Laskin, JD. Distinct effects of form selective cytochrome P450 inhibitors on cytochrome P450-mediated monooxygenase and hydrogen peroxide generating NADPH oxidase. Toxicol Appl Pharmacol. 2022; :116258. PubMed PMID:36174671 .

Joseph, LB, Gordon, MK, Zhou, P, Hahn, RA, Lababidi, H, Croutch, CR, Sinko, PJ, Heck, DE, Laskin, DL, Laskin, JD. Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix. Exp Mol Pathol. 2022;128 :104807. PubMed PMID:35798063 .

Jan, YH, Heck, DE, An, Y, Laskin, DL, Laskin, JD. Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes. Chem Res Toxicol. 2022;35 (4):636-650. PubMed PMID:35312310 PubMed Central PMC9491701.

Joseph, LB, Gordon, MK, Kang, J, Croutch, CR, Zhou, P, Heck, DE, Laskin, DL, Laskin, JD. Characterization of the rabbit conjunctiva: Effects of sulfur mustard. Exp Mol Pathol. 2021;121 :104656. PubMed PMID:34081961 PubMed Central PMC9006340.

Mishin, V, Heck, DE, Laskin, DL, Laskin, JD. The amplex red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxide in the presence of NAD(P)H. Free Radic Res. 2020;54 (8-9):620-628. PubMed PMID:32912004 PubMed Central PMC7874521.

Guillon, C, Vetrano, AM, Saxena, J, Hunter, A, Verderone, G, Finetti, TM, Wisnoski, J, DeMatteo, PW, Rapp, RD, Heindel, ND, Joseph, LB, Heck, DE, Laskin, JD. Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors. Bioorg Chem. 2020;103 :104128. PubMed PMID:32745761 PubMed Central PMC7819682.

Laskin, JD, Wahler, G, Croutch, CR, Sinko, PJ, Laskin, DL, Heck, DE, Joseph, LB. Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Exp Mol Pathol. 2020;115 :104470. PubMed PMID:32445752 PubMed Central PMC7374066.

Jan, YH, Heck, DE, Laskin, DL, Laskin, JD. DNA damage signaling in the cellular responses to mustard vesicants. Toxicol Lett. 2020;326 :78-82. PubMed PMID:32173488 PubMed Central PMC7224631.

Wahler, G, Heck, DE, Heindel, ND, Laskin, DL, Laskin, JD, Joseph, LB. Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard. Exp Mol Pathol. 2020;114 :104410. PubMed PMID:32113906 PubMed Central PMC7237310.

Guillon, C, Jan, YH, Heck, DE, Mariano, TM, Rapp, RD, Jetter, M, Kardos, K, Whittemore, M, Akyea, E, Jabin, I, Laskin, JD, Heindel, ND. Phototoxicity of 7-oxycoumarins with keratinocytes in culture. Bioorg Chem. 2019;89 :103014. PubMed PMID:31170642 PubMed Central PMC6656587.

More Publications