Lauren Aleksunes, Pharm.D., Ph.D.

Investigator
Professor, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University

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Recent Publications

Veiga-Lopez, A, Elkin, ER, Harris, SM, Blake, BE, Paquette, AG, Aleksunes, LM, Stapleton, PA. Current approaches and advances in placental toxicology. Trends Endocrinol Metab. 2025; :. PubMed PMID:40473500 .

Henry, ZR, Armstrong, L, Maliha, S, Jia, X, Gao, S, Taylor, RE, Basaly, V, Otersen, K, Yang, Z, Rizzolo, D, Stofan, M, Meadows, V, Bhattacharya, A, Zhou, P, Yang, I, Brinker, A, Zhou, L, Zhu, H, Joseph, LB, Buckley, B, Anthony, T, Aleksunes, L, Kong, B, Guo, GL. Deletion of hepatic FXR leads to more severe MASH development in female mice. Hepatol Commun. 2025;9 (6):. PubMed PMID:40377496 PubMed Central PMC12088634.

Wang, T, Jia, X, Aleksunes, LM, Shen, H, Deng, HW, Zhu, H. Developmental toxicity: artificial intelligence-powered assessments. Trends Pharmacol Sci. 2025;46 (6):486-502. PubMed PMID:40374415 PubMed Central PMC12145233.

Rivera-Núñez, Z, Kinkade, C, Brinker, A, Zhang, R, Buckley, B, Brunner, J, Ohman-Strickland, P, Qiu, X, Qasem, RJ, Fallon, JK, Smith, PC, Miller, RK, Salafia, CS, O'Connor, TG, Aleksunes, LM, Barrett, ES. Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes. Environ Health Perspect. 2025;133 (5):57001. PubMed PMID:40126888 PubMed Central PMC12052082.

Asby, SC, Thompson, LE, Goedken, M, Lucia, SM, Dominguez, AT, Kar, A, Pitts, TM, Kiseljak-Vassiliades, K, Lang, J, Aleksunes, LM, Joy, MS. Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model. Kidney Int. 2025;107 (5):930-934. PubMed PMID:39922378 PubMed Central PMC12121629.

Thompson, LE, Ghimire, A, Wen, X, Kim, C, Choza, J, Doherty, CL, Buckley, BT, Bowles, DW, O'Bryant, CL, Pfister, DG, Jaimes, EA, Aleksunes, LM, Joy, MS. A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule-1 Biomarker. J Pharmacol Clin Toxicol. 2024;12 (1):. PubMed PMID:39726772 PubMed Central PMC11671133.

Thompson, LE, Ghimire, A, Wen, X, Kim, C, Doherty, CL, Buckley, BT, Bowles, DW, O'Bryant, CL, Jaimes, EA, Aleksunes, LM, Joy, MS. Population Pharmacokinetic Model of Platinum Disposition in Cancer Patients Receiving Cisplatin and Randomized to 5-HT3 Antagonist Antiemetic Drugs. J Clin Pharmacol. 2025;65 (6):763-778. PubMed PMID:39711135 PubMed Central PMC12116245.

Toth, E, Li, H, Frost, K, Sample, P, Jilek, J, Greenfield, S, You, D, Kozlosky, D, Goedken, M, Paine, MF, Aleksunes, L, Cherrington, N. Nonalcoholic steatohepatitis increases plasma retention of sorafenib-glucuronide in a mouse model by altering hepatocyte hopping. Acta Pharm Sin B. 2024;14 (11):4874-4882. PubMed PMID:39664440 PubMed Central PMC11628858.

Kinkade, CW, Rivera-Núñez, Z, Brinker, A, Buckley, B, Waysack, O, Kautz, A, Meng, Y, Ohman Strickland, P, Block, R, Groth, SW, O'Connor, TG, Aleksunes, LM, Barrett, ES. Urinary mycoestrogens and gestational weight gain in the UPSIDE pregnancy cohort. Environ Health. 2024;23 (1):103. PubMed PMID:39567992 PubMed Central PMC11580541.

Kinkade, CW, Brinker, A, Buckley, B, Waysack, O, Fernandez, ID, Kautz, A, Meng, Y, Shi, H, Brunner, J, Ohman-Strickland, P, Groth, SW, O'Connor, TG, Aleksunes, LM, Barrett, ES, Rivera-Núñez, Z. Sociodemographic and dietary predictors of maternal and placental mycoestrogen concentrations in a US pregnancy cohort. J Expo Sci Environ Epidemiol. 2025;35 (3):382-392. PubMed PMID:39363096 PubMed Central PMC11968447.

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