Lauren Aleksunes, Pharm.D., Ph.D.

Investigator
Professor, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University

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Recent Publications

Jia, X, Wen, X, Russo, DP, Aleksunes, LM, Zhu, H. Mechanism-driven modeling of chemical hepatotoxicity using structural alerts and an in vitro screening assay. J Hazard Mater. 2022;436 :129193. PubMed PMID:35739723 PubMed Central PMC9262097.

Hafey, MJ, Aleksunes, LM, Bridges, CC, Brouwer, KR, Chien, HC, Leslie, EM, Hu, S, Li, Y, Shen, J, Sparreboom, A, Sprowl, J, Tweedie, D, Lai, Y. Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4. Clin Pharmacol Ther. 2022;112 (3):527-539. PubMed PMID:35546260 .

George, B, Szilagyi, JT, Joy, MS, Aleksunes, LM. Regulation of renal calbindin expression during cisplatin-induced kidney injury. J Biochem Mol Toxicol. 2022;36 (7):e23068. PubMed PMID:35403300 PubMed Central PMC9296602.

Memon, N, Lee, CW, Herdt, A, Weinberger, BI, Hegyi, T, Carayannopoulos, MO, Aleksunes, LM, Guo, GL, Griffin, IJ. Suppression of Bile Acid Synthesis in a Preterm Infant Receiving Prolonged Parenteral Nutrition. J Clin Exp Hepatol. ;12 (1):200-203. PubMed PMID:35068799 PubMed Central PMC8766543.

Kozlosky, D, Barrett, E, Aleksunes, LM. Regulation of Placental Efflux Transporters during Pregnancy Complications. Drug Metab Dispos. 2022;50 (10):1364-1375. PubMed PMID:34992073 PubMed Central PMC9513846.

Meakin, C, Barrett, ES, Aleksunes, LM. Extravillous trophoblast migration and invasion: Impact of environmental chemicals and pharmaceuticals. Reprod Toxicol. 2022;107 :60-68. PubMed PMID:34838982 PubMed Central PMC8760155.

Ciallella, HL, Russo, DP, Aleksunes, LM, Grimm, FA, Zhu, H. Revealing Adverse Outcome Pathways from Public High-Throughput Screening Data to Evaluate New Toxicants by a Knowledge-Based Deep Neural Network Approach. Environ Sci Technol. 2021;55 (15):10875-10887. PubMed PMID:34304572 PubMed Central PMC8713073.

Abed, DA, Lee, S, Wen, X, Ali, AR, Mangipudy, V, Aleksunes, LM, Hu, L. Optimization of 1,4-bis(arylsulfonamido)naphthalene-N,N'-diacetic acids as inhibitors of Keap1-Nrf2 protein-protein interaction to suppress neuroinflammation. Bioorg Med Chem. 2021;44 :116300. PubMed PMID:34252790 PubMed Central PMC8349900.

George, B, Wen, X, Jaimes, EA, Joy, MS, Aleksunes, LM. In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs. Int J Mol Sci. 2021;22 (12):. PubMed PMID:34208557 PubMed Central PMC8234231.

Hong, TS, Briscese, K, Yuan, M, Deshpande, K, Aleksunes, LM, Brunetti, L. Renoprotective Effects of Melatonin against Vancomycin-Related Acute Kidney Injury in Hospitalized Patients: a Retrospective Cohort Study. Antimicrob Agents Chemother. 2021;65 (9):e0046221. PubMed PMID:34152824 PubMed Central PMC8370200.

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