Lauren Aleksunes, Pharm.D., Ph.D.
Investigator
Professor, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University
Recent Publications
Zhang, R, Walker, L, Wen, X, Doherty, C, Gorczyca, L, Buckley, B, Barrett, ES, Aleksunes, LM. Placental BCRP transporter reduces cadmium accumulation and toxicity in immortalized human trophoblasts. Reprod Toxicol. 2023;121 :108466. PubMed PMID:37660740 .
Russo, DP, Aleksunes, LM, Goyak, K, Qian, H, Zhu, H. Integrating Concentration-Dependent Toxicity Data and Toxicokinetics To Inform Hepatotoxicity Response Pathways. Environ Sci Technol. 2023;57 (33):12291-12301. PubMed PMID:37566783 PubMed Central PMC10448720.
Rivera-Núñez, Z, Hansel, M, Capurro, C, Kozlosky, D, Wang, C, Doherty, CL, Buckley, B, Ohman-Strickland, P, Miller, RK, O'Connor, TG, Aleksunes, LM, Barrett, ES. Prenatal Cadmium Exposure and Maternal Sex Steroid Hormone Concentrations across Pregnancy. Toxics. 2023;11 (7):. PubMed PMID:37505555 PubMed Central PMC10384739.
Kozlosky, D, Lu, A, Doherty, C, Buckley, B, Goedken, MJ, Miller, RK, Barrett, ES, Aleksunes, LM. Cadmium reduces growth of male fetuses by impairing development of the placental vasculature and reducing expression of nutrient transporters. Toxicol Appl Pharmacol. 2023;475 :116636. PubMed PMID:37487938 PubMed Central PMC10528997.
Lazofsky, A, Brinker, A, Gupta, R, Barrett, E, Aleksunes, LM, Rivera-Núñez, Z, Buckley, B. Optimized extraction and analysis methods using liquid chromatography-tandem mass spectrometry for zearalenone and metabolites in human placental tissue. Heliyon. 2023;9 (6):e16940. PubMed PMID:37484340 PubMed Central PMC10361036.
Mosquera, AM, Aleksunes, LM. Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website. CourseSource. 2023;10 :. PubMed PMID:37476533 PubMed Central PMC10357923.
Coyte, RM, Darrah, T, Olesik, J, Barrett, E, O'Connor, TG, Brunner, J, Love, T, Perez-D'Gregorio, R, Wang, HZ, Aleksunes, LM, Buckley, B, Doherty, C, Miller, RK. Gadolinium during human pregnancy following administration of gadolinium chelate before pregnancy. Birth Defects Res. 2023;115 (14):1264-1273. PubMed PMID:37334869 .
Chung, E, Russo, DP, Ciallella, HL, Wang, YT, Wu, M, Aleksunes, LM, Zhu, H. Data-Driven Quantitative Structure-Activity Relationship Modeling for Human Carcinogenicity by Chronic Oral Exposure. Environ Sci Technol. 2023;57 (16):6573-6588. PubMed PMID:37040559 PubMed Central PMC10134506.
Barrett, ES, Rivera-Núñez, Z, Getz, K, Ohman-Strickland, P, Zhang, R, Kozlosky, D, Doherty, CL, Buckley, BT, Brunner, J, Miller, RK, O'Connor, TG, Aleksunes, LM. Protective role of the placental efflux transporter BCRP/ABCG2 in the relationship between prenatal cadmium exposure, placenta weight, and size at birth. Environ Res. 2023;225 :115597. PubMed PMID:36863650 PubMed Central PMC10091184.
Meakin, C, Kim, C, Lampert, T, Aleksunes, LM. High-throughput screening of toxicants that modulate extravillous trophoblast migration. Toxicol Lett. 2023;375 :1-7. PubMed PMID:36535517 PubMed Central PMC9877196.
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