Lauren Aleksunes, Pharm.D., Ph.D.

Investigator
Professor, Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University

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Recent Publications

Gutgarts, V, Gerardine, S, Shingarev, RA, Knezevic, A, Zabor, EC, Latcha, S, Joy, MS, Aleksunes, LM, Jaimes, EA. Evaluation of Cisplatin-Induced Acute Kidney Injury in Patients Co-Prescribed Serotonin Receptor Antagonists: A Retrospective Analysis. Kidney360. 2024; :. PubMed PMID:38814726 .

Chung, E, Wen, X, Jia, X, Ciallella, HL, Aleksunes, LM, Zhu, H. Hybrid non-animal modeling: A mechanistic approach to predict chemical hepatotoxicity. J Hazard Mater. 2024;471 :134297. PubMed PMID:38677119 .

Galetin, A, Brouwer, KLR, Tweedie, D, Yoshida, K, Sjöstedt, N, Aleksunes, L, Chu, X, Evers, R, Hafey, MJ, Lai, Y, Matsson, P, Riselli, A, Shen, H, Sparreboom, A, Varma, MVS, Yang, J, Yang, X, Yee, SW, Zamek-Gliszczynski, MJ, Zhang, L, Giacomini, KM. Membrane transporters in drug development and as determinants of precision medicine. Nat Rev Drug Discov. 2024;23 (4):255-280. PubMed PMID:38267543 .

Kozlosky, D, Doherty, C, Buckley, B, Goedken, MJ, Miller, RK, Huh, DD, Barrett, ES, Aleksunes, LM. Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter. Toxicol Sci. 2023;197 (2):132-46. PubMed PMID:37941438 PubMed Central PMC10823776.

Zhang, R, Walker, L, Wen, X, Doherty, C, Gorczyca, L, Buckley, B, Barrett, ES, Aleksunes, LM. Placental BCRP transporter reduces cadmium accumulation and toxicity in immortalized human trophoblasts. Reprod Toxicol. 2023;121 :108466. PubMed PMID:37660740 PubMed Central PMC10591833.

Russo, DP, Aleksunes, LM, Goyak, K, Qian, H, Zhu, H. Integrating Concentration-Dependent Toxicity Data and Toxicokinetics To Inform Hepatotoxicity Response Pathways. Environ Sci Technol. 2023;57 (33):12291-12301. PubMed PMID:37566783 PubMed Central PMC10448720.

Rivera-Núñez, Z, Hansel, M, Capurro, C, Kozlosky, D, Wang, C, Doherty, CL, Buckley, B, Ohman-Strickland, P, Miller, RK, O'Connor, TG, Aleksunes, LM, Barrett, ES. Prenatal Cadmium Exposure and Maternal Sex Steroid Hormone Concentrations across Pregnancy. Toxics. 2023;11 (7):. PubMed PMID:37505555 PubMed Central PMC10384739.

Kozlosky, D, Lu, A, Doherty, C, Buckley, B, Goedken, MJ, Miller, RK, Barrett, ES, Aleksunes, LM. Cadmium reduces growth of male fetuses by impairing development of the placental vasculature and reducing expression of nutrient transporters. Toxicol Appl Pharmacol. 2023;475 :116636. PubMed PMID:37487938 PubMed Central PMC10528997.

Lazofsky, A, Brinker, A, Gupta, R, Barrett, E, Aleksunes, LM, Rivera-Núñez, Z, Buckley, B. Optimized extraction and analysis methods using liquid chromatography-tandem mass spectrometry for zearalenone and metabolites in human placental tissue. Heliyon. 2023;9 (6):e16940. PubMed PMID:37484340 PubMed Central PMC10361036.

Mosquera, AM, Aleksunes, LM. Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website. CourseSource. 2023;10 :. PubMed PMID:37476533 PubMed Central PMC10357923.

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