Diane Heck, Ph.D.

Pharmacology & Drug Development
Professor & Associate Dean for Research, School of Health Sciences and Practice, New York Medical College

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Recent Publications

Laskin, JD, Ozkuyumcu, K, Zhou, P, Croutch, CR, Heck, DE, Laskin, DL, Joseph, LB. Skin Models Used to Define Mechanisms of Action of Sulfur Mustard. Disaster Med Public Health Prep. 2023;17 :e551. PubMed PMID:37849329 PubMed Central PMC11420828.

Mishin, V, Heck, DE, Jan, YH, Richardson, JR, Laskin, JD. Distinct effects of form selective cytochrome P450 inhibitors on cytochrome P450-mediated monooxygenase and hydrogen peroxide generating NADPH oxidase. Toxicol Appl Pharmacol. 2022;455 :116258. PubMed PMID:36174671 .

Joseph, LB, Gordon, MK, Zhou, P, Hahn, RA, Lababidi, H, Croutch, CR, Sinko, PJ, Heck, DE, Laskin, DL, Laskin, JD. Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix. Exp Mol Pathol. 2022;128 :104807. PubMed PMID:35798063 PubMed Central PMC10044521.

Jan, YH, Heck, DE, An, Y, Laskin, DL, Laskin, JD. Nitrogen Mustard Alkylates and Cross-Links p53 in Human Keratinocytes. Chem Res Toxicol. 2022;35 (4):636-650. PubMed PMID:35312310 PubMed Central PMC9491701.

Joseph, LB, Gordon, MK, Kang, J, Croutch, CR, Zhou, P, Heck, DE, Laskin, DL, Laskin, JD. Characterization of the rabbit conjunctiva: Effects of sulfur mustard. Exp Mol Pathol. 2021;121 :104656. PubMed PMID:34081961 PubMed Central PMC9006340.

Mishin, V, Heck, DE, Laskin, DL, Laskin, JD. The amplex red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxide in the presence of NAD(P)H. Free Radic Res. 2020;54 (8-9):620-628. PubMed PMID:32912004 PubMed Central PMC7874521.

Guillon, C, Vetrano, AM, Saxena, J, Hunter, A, Verderone, G, Finetti, TM, Wisnoski, J, DeMatteo, PW, Rapp, RD, Heindel, ND, Joseph, LB, Heck, DE, Laskin, JD. Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors. Bioorg Chem. 2020;103 :104128. PubMed PMID:32745761 PubMed Central PMC7819682.

Laskin, JD, Wahler, G, Croutch, CR, Sinko, PJ, Laskin, DL, Heck, DE, Joseph, LB. Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Exp Mol Pathol. 2020;115 :104470. PubMed PMID:32445752 PubMed Central PMC7374066.

Jan, YH, Heck, DE, Laskin, DL, Laskin, JD. DNA damage signaling in the cellular responses to mustard vesicants. Toxicol Lett. 2020;326 :78-82. PubMed PMID:32173488 PubMed Central PMC7224631.

Wahler, G, Heck, DE, Heindel, ND, Laskin, DL, Laskin, JD, Joseph, LB. Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard. Exp Mol Pathol. 2020;114 :104410. PubMed PMID:32113906 PubMed Central PMC7237310.

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